First Detection of a Carbapenem-Hydrolyzing Metalloenzyme in an Enterobacteriaceae Isolate in France

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First detection of a carbapenem-hydrolyzing metalloenzyme in an Enterobacteriaceae isolate in France.

Although many -lactamases with expanded spectra have been described for the Enterobacteriaceae, carbapenemases remain infrequent. Acquired carbapenemases of the metalloenzyme group (Ambler class B) are mostly either of the IMP or the VIM type. The VIM enzymes were reported first from Verona in Italy (VIM-1) and are scattered now in southern Europe, South America, and Southeast Asia (6). Our gro...

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Carbapenem-hydrolyzing metallo-beta-lactamase from a nosocomial isolate of Pseudomonas aeruginosa in France.

References 1. Gubler DJ, Kuno G. Dengue and dengue hemorrhagic fever. Center for Agriculture and Biosciences International; 1997; p. 10-25. 2. Henchal EA, Gentry M, McCown JM, Brandt WE. Dengue virus specific and flavivirus group determinants identified with monoclonal antibodies by indirect immunofluorescence. Am J Trop Med Hyg 1982;31:830-6. 3. Lanciotti RS, Calisher CH, Gubler DJ, Chang GJ, ...

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Plasmid-mediated carbapenem-hydrolyzing beta-lactamase KPC in a Klebsiella pneumoniae isolate from France.

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Characterization of VIM-2, a carbapenem-hydrolyzing metallo-beta-lactamase and its plasmid- and integron-borne gene from a Pseudomonas aeruginosa clinical isolate in France.

Pseudomonas aeruginosa COL-1 was identified in a blood culture of a 39-year-old-woman treated with imipenem in Marseilles, France, in 1996. This strain was resistant to beta-lactams, including ureidopenicillins, ticarcillin-clavulanic acid, cefepime, ceftazidime, imipenem, and meropenem, but remained susceptible to the monobactam aztreonam. The carbapenem-hydrolyzing beta-lactamase gene of P. a...

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ژورنال

عنوان ژورنال: Antimicrobial Agents and Chemotherapy

سال: 2004

ISSN: 0066-4804,1098-6596

DOI: 10.1128/aac.48.12.4929-4930.2004